Aliskiren represents a new principle of blocking the RAAS, inhibiting renin directly and acting at the rate-limiting step. 阿利吉仑代表一种阻滞RAAS的新原理,直接抑制肾素并作用于限速阶段。
The C-H bond activation is the rate-limiting step. C-H键活化为整个反应的决速步骤。
Hydrolysis to amino acid was a rate-limiting step for protein anaerobic degradation; 蛋白质水解为氨基酸是蛋白质类物质厌氧处理的限速步骤;
Taxadiene synthase is the first known, and the most important, enzyme involved in taxol anabolism, which catalyzes the first committed, and a slow but not rate-limiting, step of taxol biosynthesis. 紫杉二烯合成酶是第一个被详细研究和目前所发现的最重要的紫杉醇合成代谢酶,它催化紫杉醇生物合成途径中的第一个定向的、慢速的步骤,然而该步骤并非限速步骤。
The results indicated that the association/ dissociation kinetics between IgG and protein G affinity packings became the rate-limiting step in perfusion affinity chromatographic separation process. 结果表明,对于小鼠血清中的IgG灌注亲和色谱的分离,由于解离速率影响到传质过程,使之在高流速下的分离受到一定的限制。
The translocation of cholesterol from the out to the inner mitochondrial membrane is a rate-limiting step that requires steroidogenic acute regulator protein ( StAR) synthesis de novo in steroidogenesis. 在类固醇激素的合成过程中,胆固醇由线粒体外膜到内膜转运的过程是类固醇激素合成的限速步骤,这一步骤必需有类固醇激素灵敏调节蛋白(StAR)的从头合成才能完成。
The formation of ADP-Glucose is a rate-limiting step during starch synthesis. This equilibrium is directly regulated by the supplement of ATP as a substrate, which in turn definite influences the character of plant starch. ADP-葡萄糖(ADPG)的形成是淀粉合成的限速步骤,该反应平衡受底物ATP供给水平调控,最终影响植物淀粉性状。
The rate-limiting step of the electrode process at high Po_2 is the diffussion of oxygen atom into the solid electrolyte on the triple line. 在高氧分压下,电极过程由氧原子在三相线发生反应后直接进入电解质步骤控制;
The a-amide comes from posttranslational modification that is catalyzed by α-amidase(α-AE or PAM). The amidation reaction is a rate-limiting step in the biosynthesis of regulatory peptides. α-酰胺基来自多肽的翻译后加工,由α-酰胺化酶(α-AE或PAM)催化完成,是酰胺化多肽生物合成途径中的限述步骤。
ENaC is responsible for the rate-limiting step of sodium reabsorption and thus plays an important role in the maintenance of sodium balance, extracellular fluid volume and blood pressure. ENaC负责钠离子的限速重吸收,对于维持钠的自身平衡、细胞外液量和血压起重要作用。
But T-DNA integration other than T-DNA transfer and nuclear targeting remains to be the rate-limiting step in Agrobacterium-mediated transformation of indica rice. 2. 但籼稻中农杆菌介导的遗传转化的限速步骤依然是T-DNA整合。
How to improve the clinical pregnancy rate has consistently been the goal of clinicians. In a number of factors that affect the outcome of IVF-ET, embryo implantation is considered to be the rate-limiting step of successful pregnancy. 如何提高IVF-ET治疗的成功率始终是临床工作者不断追求的目标。在影响其结局的诸多因素中,胚胎着床被认为是妊娠成功的主要限速步骤。
Heme oxygenase ( HO) is an enzyme that catalyzes the rate-limiting step in the degradation of heme to biliverdin, carbon monoxide and iron. 血红素氧化酶(HO)降解血红素生成胆绿素、一氧化碳和游离铁,是血红素代谢反应过程中的限速酶。
Cholesterol delivery to the mitochondrial inner membrane is believed to be a rate-limiting step for the acidic pathway of bile acid synthesis. 胆固醇进入线粒体内膜被认为是胆汁酸合成酸性通路的限速步骤。
The rate-limiting step of the method is an anaerobic treatment process. Recent studies showed that redox mediators could effectively accelerate the process. 此方法的限制步骤为厌氧处理阶段,而氧化还原介体可以有效加速此过程,从而提高处理效率。
The corresponding activation energy is slightly higher than that of the rate-limiting step in the stepwise mechanism. It is proposed that there should be a competition between two reaction mechanisms. 该过程的活化能略低于分步反应过程的速控步骤,这意味着这两个机理之间存在竞争。
The one-electron mechanism is predicted to be spin-conserved and the rate-limiting step is the cleavage of the O-H bond with 27.92 kcal/ mol energy barrier. 计算结果表明,单电子机理是自旋守恒的,其决速步骤为第一步中的O-H键断裂,活化能为27.92kcal/mol。
Hydrolysis is considered as rate-limiting step of anaerobic digestion, thus pretreatments are adopted to accelerate the hydrolysis rate. 水解作为污泥厌氧消化的限速步骤,需要通过预处理加快水解速率。
Heme oxygenase ( HO) catalyzes the rate-limiting step in the degradation of heme. 血红素加氧酶(HemeOxygenase,HO)是血红素代谢的限速酶。
Our calculations indicated that the total reaction is stepwise and exothermic, and that the rate-limiting step is to overcome the barrier ( 9.36 kcal/ mol) in the second step. 计算结果表明,整个反应是一个放热过程,第二步反应是整个反应过程的决速步骤,反应能垒为9.36kcal/mol。
The process that ammonia-oxidizing bacteria catalyzed nitrosation is rate-limiting step of nitrification, and it plays an important role in natural geochemical cycling of nitrogen. Therefore in microbial ecology, AOB has been proposed as a model organism. 氨氧化细菌催化的亚硝化过程为硝化作用的限速步骤,在自然界氮素地球化学循环过程中起着重要的作用,因此在微生物生态学中,已经建议将其作为一种模式生物。
In which the ethylene protonation shows the highest energy barrier and is confirmed as the rate-limiting step. 其中乙烯质子化反应能垒最高,为速控步骤。